From 1754 to 1815, the British worked with and against the North American Indians (hereinafter, Indians) to determine who would eventually control the Trans-Appalachian West to the Mississippi River from the Laurentian Great Lakes through the Ohio River Valley to the Gulf of Mexico. This era is being redefined as the Sixty Years’ War to highlight its importance to the Indians of the area and how the wars of the period could be seen from a different lens than the Euro-centric.